Background Immune checkpoint blockers (ICBs) have been approved by the Food and Drug Administration to be used alone in front-line therapies or in combination with other regimens for certain advanced cancers.Since ICB only works in a subset of patients and has limited efficacy in treating ovarian cancer (OVC), developing preclinical models that hel
A fast three-dimensional (3D) node localization algorithm in multipath for ultra-wideband (UWB) wireless sensor networks is developed.The algorithm employs a modified propagator peperomia double duty method (MPM) for time delay estimation and then uses a marriage algorithm of 3D Chan and Taylor for range-based multilateral localization and node pos
Web application frameworks and ORM tools reduce time and effort needed when developing quality applications; but, since they are numerous and heterogeneous choosing the best suited is not an easy task.The comparative studies of these tools do not consider case studies of the necessary complexity to precisely measure their advantages and disadvantag
Cathepsin-like enzymes have been identified as potential targets for drug or vaccine development in many parasites, as their functions appear to be essential in a elbeco adu ripstop pants variety of important biological processes within the host, such as molting, cuticle remodeling, embryogenesis, feeding and immune evasion.Functional analysis of C